Headaches when I play!

About a year ago I started getting really bad migraines and nausea when I played. I messed with some setting but I haven’t been able to get it right… I can play for a max of 5 minutes before it starts, but I have no problem watching let’s play videos…. I think it must just be how I have my game set up. Does anyone know of some resources or settings I can use to help?