Ever have a job just not work out?

I assume we all have at least some competence at our craft, or we wouldn't be here. As a consultant, I've been through the ritual of starting a new client, being lost my first day, gradually learning the lay of the land, onboarding and getting my bearings. 98% of the time I get in my groove within a few weeks and it's smooth sailing after.

But have you ever had a gig where, for one reason or another, you just never seemed to get off the launch pad? Perhaps the place was so disorganized that onboarding was like pulling teeth, or the tech stack was far different from your realm of expertise, or something else made things just not "go." How did you handle it? Did you finally make it work out or did you split amicably?

UPDATE: Thanks for your kind responses. If it wasn't obvious, I recently had an experience like this. I was laid off in October and immediately read all these Reddit posts about "Worst tech job market since the dotcom crash!" I was understandably concerned, since I'm my family's primary breadwinner.

I found a contract, but there were many red flags. Under normal circumstances, I wouldn't have taken it, but I was under duress. It turns out I detected those red flags for a reason. I was very lucky in that I reconnected with another company and it turned out they needed one more developer. I aced the interview and am on a much better team now. I quit that first contract in two months. I just didn't see a point in continuing the stress and frustration when it was not going to work out.